The Castine Center is centrally located to a number of interstate highway systems that traverse our country. As a point of reference you will find Birmingham, AL & Meridian, MS to the Northeast. Jackson & Hattiesburg, MS to the North. Biloxi, MS, Mobile, AL and Pensacola, FL to the East. Baton Rouge, LA and Houston, TX to the West. With New Orleans being due South across Lake Pontchartrain.